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2-Hydroxyethyl methacrylate (HEMA)

  • Product Name: 2-Hydroxyethyl methacrylate (HEMA)
  • CAS: 868-77-9
  • Purity:
  • Appearance: colourless liquid

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  • Molecular Formula:C6H10O3
  • Molecular Weight:130.144
  • Appearance/Colour:colourless liquid 
  • Vapor Pressure:0.01 mm Hg ( 25 °C) 
  • Melting Point:-12 °C 
  • Refractive Index:n20/D 1.453(lit.)  
  • Boiling Point:189.031 °C at 760 mmHg 
  • PKA:13.83±0.10(Predicted) 
  • Flash Point:97.222 °C 
  • PSA:46.53000 
  • Density:1.054 g/cm3 
  • LogP:0.09800 

2-Hydroxyethyl methacrylate(Cas 868-77-9) Usage

Definition

2-Hydroxyethyl methacrylate is an enoate ester that is the monomethacryloyl derivative of ethylene glycol.

General Description

2-Hydroxyethyl methacrylate (HEMA) is biocompatible in nature. Polymeric hydrogel scaffold can be produced by polymerizing HEMA in water.

Hazard

30% grade (with xylene): Flammable, moderate fire risk.

Purification Methods

Dissolve the ester in water and extract with n-heptane to remove ethylene glycol dimethacrylate (checked by gas-liquid chromatography and by NMR) and distil it twice under reduced pressure [Strop et al. J Phys Chem 80 694 1976]. [Beilstein 2 IV 1530.]

InChI:InChI=1/C6H10O3/c1-4(2)6(8)9-5(3)7/h5,7H,1H2,2-3H3

868-77-9 Relevant articles

BIOGUM AND BOTANICAL GUM HYDROGEL BIOINKS FOR THE PHYSIOLOGICAL 3D BIOPRINTING OF TISSUE CONSTRUCTS FOR IN VITRO CULTURE AND TRANSPLANTATION

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, (2021/01/20)

Bioink compositions comprising a biomate...

Acrylate monomer having hydrophilic end group and a method for preparing the same

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Paragraph 0093-0106; 0128-0132, (2021/11/02)

More particularly, the present invention...

Runge-Kutta analysis for optimizing the Zn-catalyzed transesterification conditions of MA and MMA with diols to maximize monoesterified products

Kato, Taito,Akebi, Shin-Ya,Nagae, Haruki,Yonehara, Koji,Oku, Tomoharu,Mashima, Kazushi

, p. 6975 - 6986 (2021/11/17)

Terminal hydroxylated acrylates and meth...

Method for producing hydroxyethyl methacrylate through ester exchange method

-

Paragraph 0015-0045, (2019/01/23)

The invention discloses a method for pro...

868-77-9 Process route

oxirane
75-21-8,99932-75-9

oxirane

poly(methacrylic acid)
79-41-4,25087-26-7,50867-57-7

poly(methacrylic acid)

2-methyl-2-propenoic acid 2-hydroxyethyl ester
868-77-9,141668-69-1,25736-86-1,82601-55-6,25249-16-5

2-methyl-2-propenoic acid 2-hydroxyethyl ester

2-hydroxyethyl acetate
542-59-6

2-hydroxyethyl acetate

2-(2-hydroxyethoxy)ethyl methacrylate
2351-43-1,25736-86-1

2-(2-hydroxyethoxy)ethyl methacrylate

EDMA
97-90-5,12738-39-5

EDMA

Conditions
Conditions Yield
10H-phenothiazine; chromium(lll) acetate; at 60 - 80 ℃; for 6.1h; under 750.075 Torr; Autoclave;
96.0 %Chromat.
0.08 %Chromat.
3.7 %Chromat.
0.3 %Chromat.
1,2-propanediene
463-49-0

1,2-propanediene

carbon monoxide
201230-82-2

carbon monoxide

ethylene glycol
107-21-1

ethylene glycol

2,2-dimethyl-1,3-dioxolane
2916-31-6

2,2-dimethyl-1,3-dioxolane

2-methyl-2-propenoic acid 2-hydroxyethyl ester
868-77-9,141668-69-1,25736-86-1,82601-55-6,25249-16-5

2-methyl-2-propenoic acid 2-hydroxyethyl ester

Conditions
Conditions Yield
dodecacarbonyl-triangulo-triruthenium; at 100 ℃; for 3h;
52%
8%

868-77-9 Upstream products

  • 75-21-8
    75-21-8

    oxirane

  • 79-41-4
    79-41-4

    poly(methacrylic acid)

  • 107-21-1
    107-21-1

    ethylene glycol

  • 80-62-6
    80-62-6

    methacrylic acid methyl ester

868-77-9 Downstream products

  • 19117-13-6
    19117-13-6

    2-Methyl-acrylic acid 2-(heptyl-{4-[1-(4-{heptyl-[2-(2-methyl-acryloyloxy)-ethoxy]-phosphinoyloxy}-phenyl)-1-methyl-ethyl]-phenoxy}-phosphinoyloxy)-ethyl ester

  • 97789-13-4
    97789-13-4

    Phosphorsaeure-diisoamylester-(2-methacryloyloxy-ethylester)

  • 814-26-6
    814-26-6

    Phosphorsaeure-diisobutylester-(2-methacryloyloxy-ethylester)

  • 15458-75-0
    15458-75-0

    2-(methacryloyloxy)ethyl phosphate

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