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N,2,3-Trimethyl-2-isopropylbutamide (Cooling agent WS-23)

  • Product Name: N,2,3-Trimethyl-2-isopropylbutamide (Cooling agent WS-23)
  • CAS: 51115-67-4
  • Purity:
  • Appearance:

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High Quality Chinese Manufacturer supply 51115-67-4 N,2,3-Trimethyl-2-isopropylbutamide (Cooling agent WS-23)

  • Molecular Formula:C10H21NO
  • Molecular Weight:171.283
  • Vapor Pressure:0.0573mmHg at 25°C 
  • Melting Point:58-61 °C 
  • Refractive Index:1.431 
  • Boiling Point:233 °C at 760 mmHg 
  • PKA:16.46±0.46(Predicted) 
  • Flash Point:132 °C 
  • PSA:29.10000 
  • Density:0.854 g/cm3 
  • LogP:2.44160 

N,2,3-Trimethyl-2-isopropylbutamide(Cas 51115-67-4) Usage

Trade name

Winsense WS-23 (Renessenz).

Aroma threshold values

Aroma characteristics at 5.0%: slight cooling impact with little character.

Taste threshold values

Taste characteristics at 20 ppm: high-impacting cooling that lasts on the tongue and palate.

InChI:InChI=1/C10H21NO/c1-7(2)10(5,8(3)4)9(12)11-6/h7-8H,1-6H3,(H,11,12)

51115-67-4 Relevant articles

Method of using solid acid catalyst to synthesize amide-type cooling agent

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Paragraph 0029-0032; 0037-0044; 0049-0060, (2019/10/04)

The invention belongs to the technical f...

Synthetic method of cooling agent N,2,3-trimethyl-2-isopropyl butylamide

-

Paragraph 0020; 0021; 0024, (2018/05/16)

The invention discloses a synthetic meth...

Method for making amides

-

, (2008/06/13)

The invention relates to the manufacture...

Lower primary alkanols and their esters in a Ritter-type reaction with nitriles. An efficient method for obtaining N-primary-alkyl amides

Lebedev, Mikhail Y.,Erman, Mark B.

, p. 1397 - 1399 (2007/10/03)

N-Primary-alkyl amides RCONHR1 were obta...

51115-67-4 Process route

methanol
67-56-1

methanol

2,2-diisopropylpropionitrile
55897-64-8

2,2-diisopropylpropionitrile

N,2,3-trimethyl-2-isopropylbutanamide
51115-67-4

N,2,3-trimethyl-2-isopropylbutanamide

Conditions
Conditions Yield
With activated PMA-SiO2 solid acid catalyst; In water; at 90 ℃; for 5h; Reagent/catalyst; Temperature;
94%
3-isopropyl-3,4-dimethyl-pentan-2-one
67029-99-6

3-isopropyl-3,4-dimethyl-pentan-2-one

N,2,3-trimethyl-2-isopropylbutanamide
51115-67-4

N,2,3-trimethyl-2-isopropylbutanamide

Conditions
Conditions Yield
With hydroxylamine hydrochloride; potassium carbonate; In tetrahydrofuran; for 2h;
49.7%

51115-67-4 Upstream products

  • 67-56-1
    67-56-1

    methanol

  • 55897-64-8
    55897-64-8

    2,2-diisopropylpropionitrile

  • 616-38-6
    616-38-6

    carbonic acid dimethyl ester

  • 67029-99-6
    67029-99-6

    3-isopropyl-3,4-dimethyl-pentan-2-one

51115-67-4 Downstream products

  • 75-93-4
    75-93-4

    methyl bisulfate

  • 51115-81-2
    51115-81-2

    2-isopropyl-2,3-dimethylbutanoyl chloride

  • 23119-04-2
    23119-04-2

    2-isopropyl-2,3-dimethylbutanoic acid

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