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Imidazole is used as a buffer in the range of pH 6.2-7.8. It is also an histamine antagonist. It acts as a chelator and forms complexes with various divalent cations. It is used as a corrosion inhibitor on certain transition metals such as copper. Its derivatives, like polybenzimidazole (PBI), act as fire retardants. It finds application in photography and electronics. Imidazole salts are used as ionic liquids and precursors to stable carbenes. Imidazole derivatives like ketoconazole, miconazole and clotrimazole are involved in the treatment of various systemic fungal infections. It is a part of the theophylline molecule, present in tea leaves and coffee beans, which stimulates the central nervous system.
2-Amino-2-methyl-1-propanol
1,1'-carbonyldiimidazole
1H-imidazole
4,4-dimethyl-1,3-oxazolidin-2-one
Conditions | Yield |
---|---|
In
diethyl ether;
for 0.166667h;
Ambient temperature;
|
94% |
1H-imidazole
benzothiazole-6-carboxylic acid
Conditions | Yield |
---|---|
|
The CAS number of Imidazole is 288-32-4.
More information of Imidazole 288-32-4 are:
CAS Number |
288-32-4 |
Density |
1.116 g/cm3 |
Melting Point |
88-91 °C(lit.) |
Boiling Point |
257 °C at 760 mmHg |
Flash Point |
145 °C |
Vapor Pressure |
<1 mm Hg ( 20 °C) |
Refractive Index |
1.4801 |
HS CODE |
29332990 |
PSA |
28.68000 |
LogP |
0.40970 |
Pka |
6.953(at 25℃) |
Synonyms for Imidazole 288-32-4:Methanimidamide, N,N-1,2-ethenediyl-;1H-Imidazole (9CI);1H-Imidazole, monohydrochloride;1,3-Diazole;1,3-Diaza-2,4-cyclopentadiene;Imidazol;Methanimidamide, N,N-1, 2-ethenediyl-;Formamidine, N,N-vinylene-;Him;IMD;Glyoxaline;1467-16-9;Glyoxalin;Iminazole;Imutex;imidazole chloride;Pyrro(b)monazole;Miazole;2-phenyl-4,5-dihydroxy metylimidazole;
The chemical formula of Imidazole is C3H4N2 which containing 3 Carbon atoms,4 Hydrogen atoms and 2 Nitrogen atoms,and the molecular weight of Imidazole is 68.0782.
Imidazole is a heterocyclic compound with a five-membered planar ring, characterized by its amphoteric and highly polar nature. It is a moderately strong base (pKb= 7.0) and a weak acid (pKa= 14.9), possessing considerable aromatic character and undergoing various electrophilic aromatic substitution reactions. Imidazole is stable at high temperatures, has antioxidant activity, and is widely found in nature, such as in histamine, histidine, and benzimidazole. It is also a part of the theophylline molecule, which is present in tea leaves and coffee beans and stimulates the central nervous system.
InChI:InChI=1/C3H4N2/c1-2-5-3-4-1/h1-3H,(H,4,5)
Relevant articles related to Imidazole:
Article |
Source |
Enthalpy Changes Accompanying Hydrolysis of 3-(2-Furyl)acryloylimidazole by α-Chymotrypsin |
Slightom, J. L.,Bolen, D. W. , p. 6318 - 6324 (1980) |
Synthesis of 1-alkylimidazoles |
Gridnev,Mihaltseva , p. 1547 - 1555 (1994) |
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